Immediate administration of significant-dose opioid agonists may transiently elevate ICP and lessen cerebral perfusion pressures. These functions are affiliated with opioid-induced reducing of imply arterial strain, which stimulates a regulatory reaction to improve cerebral blood movement resulting in greater ICP. Opioid agonist-induced respiratory despair can make cerebral hypoxia an... https://curepain.co.uk/product/fentanyl-powder-synthetic-opioid/