Patients dependent upon methadone or extended‐acting opioid merchandise can be much more vulnerable to precipitated and prolonged withdrawal all through induction than These on limited‐acting opioid goods. The concomitant utilization of buprenorphine and CYP3A4 inducers can reduce the plasma concentration of buprenorphine [see Scientific Pharmacology (twelve.3)], possibly causing decr... http://zoomgroups.comundefined