2006). Novel multi-targeted kinase inhibitors including sunitinib demonstrate activity in a few patients with imatinib-resistant GIST, but are not uniformly productive, and it really is thus essential to discover alternate signaling targets for therapies in GIST. PKCθ is a beautiful therapeutic focus on in GIST since it is expressed in https://bms-30314109876.thekatyblog.com/15484239/the-smart-trick-of-ff-10101-that-nobody-is-discussing