From the subjects with asthma, IgE antibodies particular to TDI, MDI, or hexamethylene diisocyanate (HDI) ended up only found in a single topic who was occupationally exposed. No differences during the prevalence of respiratory signs or symptoms have been located. Wilder et al. (2011) did not find a big boost https://costabull.com/product/toluene-diisocyanate-tdi-80-20/