You will find there's launch of norepinephrine from your descending inhibitory bulbospinal neurons that binds to alpha-2-receptors in the dorsal horn to reduce afferent agony transmission and create analgesia. Thus, medications like clonidine that goal alpha-2 receptors can affect the transmission of agony. On the list of theories with https://nicki258slh7.cosmicwiki.com/user