Steer clear of using fentanyl transdermal system in sufferers with critical hepatic impairment. In patients with moderate to average hepatic impairment, begin with one particular 50 % of the standard dosage of fentanyl transdermal process. Opioid antagonists should not be administered during the absence of clinically important respiratory or circulatory http://josepha333zqh3.thenerdsblog.com/profile